Circulating Reed-Steinberg Cells

The Reed-Steinberg cell: molecular characterization by proteomic analysis with therapeutic implications.

OBJECTIVE To characterize Reed-Sternberg (R-S) cells by proteomic analysis in order to gain insight into the molecular pathways that control their growth and thereby to discern potential molecular interventions in Hodgkin's disease. METHODS Ten cases of the nodular sclerosing (NS) subtype and 4 cases of the lymphocyte-predominant (LP) subtype were studied. Immunohistochemical procedures were ...

IgE in Reed-Sternberg cells.

The Steinberg Representation

Introduction. Group representations occupy a sort of middle ground between abstract groups and transformation groups, i.e., groups acting in concrete ways as permutations of sets, homeomorphisms of topological spaces, diffeomorphisms of manifolds, etc. The requirement that the elements of a group act as linear operators on a vector space limits somewhat the complexity of the action without sacr...

Steinberg groups as amalgams

For any root system and any commutative ring, we give a relatively simple presentation of a group related to its Steinberg group St. This includes the case of infinite root systems used in Kac–Moody theory, for which the Steinberg group was defined by Tits and Morita–Rehmann. In most cases, our group equals St, giving a presentation with many advantages over the usual presentation of St. This e...

The Steinberg Wiring Problem